ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS
نویسندگان
چکیده
منابع مشابه
Antifungal Prophylaxis in Immunocompromised Patients
Invasive fungal infections (IFIs) represent significant complications in patients with hematological malignancies. Chemoprevention of IFIs may be important in this setting, but most antifungal drugs have demonstrated poor efficacy, particularly in the prevention of invasive aspergillosis. Antifungal prophylaxis in hematological patients is currently regarded as the gold standard in situations w...
متن کاملA rationale for reduced-frequency dosing of anidulafungin for antifungal prophylaxis in immunocompromised patients.
OBJECTIVES Reduced-frequency dosing strategies of anidulafungin may offer a more convenient way of providing adequate antifungal prophylaxis to patients at high risk of invasive fungal diseases. We aimed to provide the pharmacological rationale for the applicability of reduced-frequency dosing regimens. METHODS We defined two groups of 10 patients that were to receive anidulafungin at 200 mg ...
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These recommendations have been developed by an expert panel following an evidencebased search of the literature assessing the role of primary antifungal prophylaxis in patients with acute leukaemia or stem cell transplantation. We present results from a questionnaire on the current practice among experts in Europe, show results of the literature search and provide the panel’s recommendations. ...
متن کاملAntifungal prophylaxis in critically ill patients
van Till and colleagues assessed yeast colonisation, lumping together ‘positive yeast cultures obtained from sputum, stool, urine and/or wound’ [1]. The majority of SDD trials reported positive yeast cultures obtained from surveillance cultures of throat and rectal swabs, whilst the SAP studies mainly assessed positive yeast cultures obtained from diagnostic samples including lower airway secre...
متن کاملCaspofungin as secondary antifungal prophylaxis and subsequent maintenance antifungal prophylaxis therapy in hematological malignancy patients.
AIM This study aimed to investigate the efficacy and safety of caspofungin as secondary antifungal prophylaxis (SAP) and subsequent maintenance therapy for SAP in hematological malignancy patients. METHODS Forty four patients receiving caspofungin for SAP and 43 patients not receiving any SAP agents during their subsequent chemotherapy or HSCT were reviewed retrospectively. The clinical chara...
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ژورنال
عنوان ژورنال: Mediterranean Journal of Hematology and Infectious Diseases
سال: 2016
ISSN: 2035-3006
DOI: 10.4084/mjhid.2016.040